Types of Inherited Colon Cancer

Colorectal cancer is more frequent. There are approximately 125,000 new cases diagnosed in America this year. Many of these cases are patients over 50 years old and are random. A small proportion, about 10%, but are not accidental, they have a hereditary form of colon cancer. This could not by four different hereditary conditions, hereditary-polyposis colon cancer, familial adenomatous polyposis, is caused Juvenile polyposis(this is also nonhereditary) and Peutz-Jegher can Syndrome.

Colorectal cancer is caused by damage to the genes in your colon cells. This damage can cause the cells to grow indefinitely. This unrestricted growth becomes a polyp, the development of cancer to be involved if they are not removed. Normally, it takes a long time for polyps to develop and even longer to become cancerous. That is why colon cancer is in men less than 50 years ago from rare. The cases infewer than 50 persons are often caused by an inherited condition.

Inherited colon cancers are difficult to accurately diagnose. It is first necessary to examine if a person is a strong family history of colorectal cancer and the families concerned have, are of different generations. For example, have - a husband, two uncles and a cousin who is diagnosed, has, it would be a strong family history. With a bit of research in these patients, family tree, many more casesCancer can be identified and documented.

The two most common inherited colon cancers are hereditary non-polyposis colon cancer (HNPCC) and familial adenomatous polyposis (FAP). Recently, the genes has lead to any of these conditions have been identified and is now developing a blood test that tells you if you have inherited the disease. This blood test, a person who has inherited the disease, can begin is always tested for colonCancer at an earlier stage than most people. These early tests can doctors, the disease at an early stage, when it catch the most treatable. It also allows a doctor to determine whether a course of chemoprevention is appropriate, or if other prevention strategies are more appropriate.

Hereditary non-polyposis colorectal cancer occurs when the gene damage interferes with cell repair. HNPCC causes about 5% of all cancer diagnosed, but it canCause other cancers as well. HNPCC can also cause cancer of the urinary tract (kidney, bladder or ureter), the female reproductive organs (uterus, endometrium, or ovaries), or) the remainder of the gastrointestinal tract (stomach, small intestine, or pancreas. A person with HNPCC has a 80% chance of cancer. Even in this high risk, regular medical checkups and cancer screenings can save your life by preventing or catching cancer screeningon.

To develop familial adenomatous polyposis causes hundreds, even thousands of polyps in the intestines of humans. As a person affected by FAP begins with the development of polyps at an early age - he or she often develops colon cancer by 40 years, ten years earlier than most doctors do not even come close screening. Therefore, it is recommend that people get with a family history of blood test for FAP.

Not much is known about Juvenile polyposis.Some forms of juvenile polyposis are hereditary, but it gives no commercial genetic test. The only test available to be used exclusively for research purposes. Juvenile polyposis often causes polyps in the colon and small intestine. If there are no symptoms are present, they are usually caused by the polyps in the colon. Surgery is often the suggested treatment in such cases.

Peutz-Jeghers syndrome is a genetic disease that causes intestinal polyps andFreckles on the skin of the mouth. There are no cases of Peutz-Jegher's freckles developing into skin cancer. The greatest risk of colorectal cancer comes from the intestinal polyps. These polyps are typically large in the small intestine and can so that it found to be an intestinal blockage. Roughly half of the Peutz-Jeghers patients require surgery for a blockage at the age of 20 years. Peutz-Jegher has also been associated with an increased risk associatedother cancers and it is recommended that all patients Jegher Puetz-begin cancer screenings at an earlier stage than the general population.

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