Addisons Disease Causes Symptoms Information With Treatment

Addison's disease (chronic adrenal insufficiency) is a rare, progressive disease, which is between one and six people per 100,000 are affected. It occurs in all age groups and affects men and women. Addison's disease is resolved with the inability of the adrenal glands, adequate amounts of hormones. The adrenal cortex (the outside) is also important hormones, corticosteroids.

Addison's disease, classical results from a loss of both cortisol andsecretion of aldosterone by the almost total or partial destruction of both adrenal glands. These glands are part of the endocrine system, which works with the nervous system and the immune system to handle the body with different events and stresses. It helps to eliminate the pressure of the blood and water and salt in the body through the kidneys retain sodium and potassium.

When aldosterone production falls too low, the kidneys are not able to regulate salt and water balance,causing blood volume and blood pressure decreases. If the ACTH deficiency will not be enough cortisol produced, although aldosterone may remain adequate. This is secondary adrenal insufficiency, the significantly different, but similar to Addison's disease, since both include a loss of cortisol secretion.

The causes of Addison's disease

The most common causes of Addison's disease:

The immune system mistakenly attacks the gland (autoimmune disease)

The use of anticoagulants Medicines (anticoagulants)

Infections such as tuberculosis, HIV, or fungal infections.

Invasion of the adrenal by cancer cells from another part of the body.

Tumors.

Chronic infections such as fungal infections.

Hemorrhage, blood loss.

The symptoms of Addison's disease are caused by cortisol, the failure of the adrenal glands, kidneys, to produce enough of sitting on the hormone, and in some cases, aldosterone.

Disease> Addison symptoms

Some symptoms of Addison's disease:

Muscle weakness.

Depression

Irritability

The chronic fatigue that gradually worsened.

Weight loss and anorexia

Nausea, vomiting or diarrhea

Dehydration.

Dysphagia (difficulty swallowing)

Polyuria

Increased numbers of eosinophils.

Agitation

The treatment of Addison's disease

to replace the drugs, cortisol, hormones andAldosterone. Hydrocortisone is widely used because it can function as both these hormones. If another drug instead of hydrocortisone (such as prednisolone, methylprednisolone, dexamethasone, or) is used, you will also need a medication that can function as aldosterone (usually fludrocortisone). You will need a higher dose of the drug during delivery, if you have an injury, surgery or a serious infection or severe stress, such as the death of a loved oneone.

The increase of salt in the diet. Because people tend to lose with adrenal insufficiency, sodium, you need extra salt (sodium chloride) in the diet, especially during the hot and humid and vigorous exercise. But because people with Addison's disease retain potassium, you should avoid salt substitutes, which usually contain potassium chloride salts.

regular checks to monitor symptoms and blood pressure. Your doctor may also need to do laboratory testsassess and monitor blood levels of potassium, sodium and cortisol.

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