Cholestatic liver disease

The term "cholestasis" literally means "cessation of bile." If the flow is disturbed bile in your body, anicteric cholestasis Compatible rise in the body. middle-aged women over 40 are suffering from chronic cholestatic liver disease. This type of disease is called "primary biliary cirrhosis."

Diagnosis

About 90 percent of patients diagnosed with primary biliary cirrhosis are women over 40 years. Women living inNorthern Europe are more susceptible to this disease than women in other parts of the world. Women in Japan have the lowest rate of diagnosed cases of this disease.

The diagnosis of cholestatic liver disease is based on a combination of many discoveries and experiments. Some of these factors are the results of cholestatic liver enzymes, positive anti-mitochondrial antibodies and characteristic liver biopsy. The most common laboratory finding is the search for elevated serumalkaline phosphates from the liver. The presence of anti-mitochondrial antibodies is the most characteristic laboratory finding in cholestatic liver disease. positive 95 percent of all those who suffer from this disease tests for anti-mitochondrial antibodies.

Signs and symptoms

Fatigue is the most common symptom of this disease. Seventy to eighty percent of all patients with this disease experience this symptom. However, usually without fatigueThe indication of the severity of the disease. As the disease progresses, other symptoms may also occur, such as high blood pressure. As the disease progresses even more, the ability to absorb fat-soluble vitamins will decrease further. As the disease progresses, autoimmune diseases begin to develop. For example, a patient with this disease begin to develop an autoimmune disease of the thyroid, and inflammatory bowel disease, when the disorder is left to progress.

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