Colon Cancer - Is it Genetic?

Awareness of genetic and other risk factors is important because there are very effective means available that could prevent most cancer morbidity and mortality. Tumorgenetics was among the first clinical applications of the methods of molecular biology. Progress in understanding the genetic basis of human disease creates opportunities, money for diagnostic and prognostic assessments at different types of analysis of the differences in a basicsingle DNA. A simple way to prevent colon cancer is early detection and colonic cleansing receive colonge health ..

Molecular diagnostics involves the study of DNA or RNA in a clinical context. The functions of nucleic acids and their encoded protein molecules from the linear sequence of monomers determined. Although the proteins they encode to develop complex three-dimensional functional conformations as a linear peptide chains are wrapped in helicalor leaflets or higher to structures, the simple primary amino acid sequences to determine the final structure and function. In the modern molecular biology research, it is now much easier to get a long nucleic acid sequence information to derive the sequence of proteins, instead of determining them directly. The functional effects on the protein encoded by mutations or sequence variations can then be discovered.

The standard family that could be covered by primary care providersremains an essential starting point for referral to a cancer genetics program for further evaluation. Molecular techniques may eventually cheap enough to justify mass screening of the entire population, as some states are already widely used for another type of disease carried mutations, especially those causing cystic fibrosis. All doctors can begin in the recognition of potential patients with hereditary colorectal cancer syndromes helpfulthrough the acquisition of a routine family history. The family may reveal features that suggest an inherited syndrome, as diagnosed with multiple cancers or other typical clinical manifestations in a family or single person, particularly tumors at an unusually early age.

Sporadic colon tumors through somatic mutations in a few critical genes accumulate in a single cell line caused. Hereditary colon cancer syndromes are caused by mutations in the same genes, toosporadic tumors, but at least one of these is an inherited, or germline mutation. Since the first mutation step has already occurred in each cell at the time of birth in the hereditary case, only one additional somatic mutation affects a single cell, sufficient to inactivate the function of genes. In contrast, sporadic cases, two different somatic mutation analysis of events require both the maternal and paternal copies of these genes in a cell before inactivate a tumordeveloped.

Advice regarding the possible risks and benefits of cancer screening and prevention procedures and a discussion of the basic elements of informed consent, in a germ-line DNA tests are obtained. Counseling to help patients and their families to understand the information provided so that they feel comfortable in the process of making an informed decision and to assist them in choosing an approach to managing their cancerRisk and help their psychosocial adjustment to the findings. The American Society of Clinical Oncology has recommended that cancer predisposition testing, if all these criteria before the probability of a positive result is very high because the patient has a strong family history of cancer or very early onset of the disease. Moreover, can be interpreted in an appropriate manner. Finally, the results will impact on the medical treatment of the patient or family.

InIn summary, colorectal cancer can be caused is by genetics. The best advice is to try to form highly qualified medical experts to offer, a specific and detailed analysis. In parallel, it is always important to have a total colon health by cleaning regularly with only natural herbal preparations. Often the tangible result of colon cleansing is an increase in energy level through better absorption of nutrients, which was previously by harmful toxins faecal blockWhich is glued to the wall of intestinal tissues. Some people who previously bloating, gas and bloating problems by cleansing the colon, unbeneficial the excessive growth of microorganisms and bacteria in the intestines to eliminate solve. This can also lead to infection and inflammation that causes the oxidation stress in the colon.

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