The flu and its complications
Recent studies have shown that the drug Tamiflu (oseltamivir) significantly reduces the likelihood of complications from influenza disease and so deadly.
Each year the flu hits one out of ten adults and three children. Epidemics of influenza usually occur seasonally - in autumn and winter months (October to April). In addition, every 10-40 years there is a risk of an influenza pandemic, when a new strain of the virus, has no immunity against humanity,that simultaneous outbreaks of flu around the world and cause a number of deaths. According to the World Health Organization, today is the probability of occurrence of an influenza pandemic is very high.
Unlike many other viral respiratory infections, the flu is particularly dangerous because it can cause complications such as bronchitis, sinusitis, otitis media, pneumonia and encephalitis, and heart attack, and can lead to hospitalization and even death.
New research findings on the drug Tamiflu to supplement the existing results of clinical trials where Tamiflu has shown a decrease of 67% of secondary complications and the real benefits of the drug in everyday clinical practice.
A study of large U.S. companies was conducted, the investigation of cases of pneumonia and heart attack (myocardial infarction) within one month after the diagnosis of patients with influenza, of which there were some non-toxic since, and the the rest were rejected Tamiflu.The patients, the drug Tamiflu, which has been observed to reduce the risk of pneumonia and heart attack than patients not taking medications.
Another study showed that treatment with Tamiflu patients hospitalized influence significantly reduces the probability of fatal outcome in patients within three days after the first symptoms of the disease began.
The drug Tamiflu is active against all influenza viruses. It works by blocking the action of the baseNeuraminidase enzyme on the virus surface. When neuraminidase is inhibited, the virus no longer exists in the cells of the vehicle and killed. So the virus is spreading and infecting other cells. Unlike other antiviral neuraminidase inhibitors against both types of influenza are effective - viruses A and B.
Tamiflu has shown clinical efficacy in the treatment of influenza in adults and children over 1 year and for the prophylaxis of influenza in adults and adolescentsover 13 years.
With the use of Tamiflu has been established:
• Relief of symptoms by 38%;
• Reduction of secondary complications, such as bronchitis, pneumonia and sinusitis - 67%;
• Reduce the duration of the flu - 37%.
In children, reduced use of the drug Tamiflu, the severity and duration of flu symptoms and 26% compared to standard drugs, the number of cases of otitis media - 44%.
The use of Tamiflu is not limited to the relief of symptomsInfluence. Objective data demonstrate that treatment with Tamiflu less secondary respiratory diseases, bronchitis, pneumonia and hospital admissions. New data show that Tamiflu reduces the risk of complications from influenza and the possibility of death.
During clinical trials the drug Tamiflu, a highly effective, well tolerated by the body and has been shown greater security.
The drug Tamiflu has been tested by the WHO against several strains of influenza, anddemonstrated its effectiveness against strains H7 and H9 avian influenza virus. Recent data have also shown the effectiveness of Tamiflu against the H5N1 avian influenza that is currently distributed in Southeast Asia.
WHO recommendations that the storage of antiviral drugs is currently the only way to ensure the availability of the required quantities of preparations for a pandemic. In recent months, the Roche company with many governments to discuss theirRequirements of Tamiflu in equity and received orders and fulfilled from about 40 countries. The size of orders from country to country. For example, France, Finland, Iceland, Ireland, Luxembourg, Netherlands, New Zealand, Norway, Switzerland and Great Britain are already doing or planning to do the necessary reserves of Tamiflu, the drug to ensure 20-40% of its population.
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