Adenosquamous Cancer Of The Uterus

The uterus or womb located inside the pelvis of a female is prone to problems such as fibroids, cervical cancer, scarring,uterine cancer and endometriosis. The uterine wall consists of various cell types.

Cancer is named according to the cells affected by it. About 95% of uterine cancer cases are where the endometrial cells lining the uterus are affected. Cancer affecting glandular cells is called an adenocarcinoma and sometimes has squamous cells - as found on the surface of the skin and cervix. Non-cancerous squamous cells are called adenocanthomas cancer and malignant ones are called adnosquamous carcinomas.

These cancers may look different under a microscope, but are often treated the same. Adenosquamous cancer of the uterus is more invasive and aggressive which can lead to more complications and a decreased cure rate (recent research and technological advances shows an improvement in rates). Symptoms are similar to that of uterine cancer and a biopsy and histology report will determine the cancer type.

Symptoms could include unusual vaginal bleeding occurring outside normal monthly periods, watery and bloody discharge in the middle of a cycle or after menopause, discomfort and bloating in the abdomen and are similar to symptoms of endometriosis and fibroids without pain. A physical examination will determine your medical status by checking for swelling in the abdomen and distortion or swelling of the uterus.The health of the uterus, ovaries and thickness of the endometrium within the uterus can be determined using transvaginal ultrasound.

After blood tests and x-rays, a D&C (Dilation and curettage procedure) may be necessary for lab analysis of tissue from inside the uterus. Causes of other uterine cancers or adenosquamous cancer are unknown. Biggest risk factors for women include menopause, infertility, overweight, high animal fat diet, high blood pressure, endometrial hyperplasion, family history of breast or bowel cancer, diabetes, prior pelvic radiation treatment and estrogen hormone replacement therapy. Treatment of this cancer is structured and becomes individualized once the reaction of the cancer to standard treatments is determined. Often removal of the uterus is required and may include the fallopian tubes and ovaries. Lymph nodes in the abdomen, the cervix and a small portion of the upper vagina may be removed if cancer is present in the muscle walls of the uterus.

Radiation may be recommended (after surgery) to kill the remaining cancer cells. External x-rays are directed to affected areas or internal radioactive implants can be used. Treatment may also include chemotherapy which kills fast growing cells (such as cancer) and is specific to certain phases of the multiplication process and types of these cells.

Estrogen can help cancer cells grow and drugs are used to block it during treatment of endomtrial cancers, adenocarcinomas and adenosquamous cancer. Side effects mimic menopause including dry skin, weight gain and hot flashes.

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